Recently, the manufacturing systems are getting more competitive due to the customized production, rapid product change and market transition. Therefore, we have researches on an event-based and distributed object-oriented component-based manufacturing system framework to model and construct the modern manufacturing systems. A distributed colored timed Petri net (DCTPN) is developed based on the original Petri net (PN). The structural properties of DCTPN are also developed. The proposed DCTPN can model the color-based manufacturing attributes and time-based properties. In addition, the distributed and modularized models can be integrated into the desired configuration, and hence are beneficial to the frequent process reengineering. The COM (component object model) server place in a DCTPN is used to model the manufacturing execution system (MES). Based on the COM server places, the DCTPN models can integrate not only the shopfloor processes horizontally but also the MES vertically. The distributed component servers of DCTPN inference engine, distributed real-time statistical process control (DSPC) and distributed order release server (DORS) are developed to demonstrate the proposed manufacturing system framework. All applications can be handled by the DTMS to illustrate the capacity of the DCOM-based, distributed transparent, fault tolerant and load balancing manufacturing systems. Finally, an IC fabrication manufacturing system and a reconfigurable cluster tool are modeled using DCTPN. In the constructed models, equipment and wafer based dispatching rules are imbedded in the DCTPN components to emulate the different production polices.